Advanced Cardiac Drug Delivery

heart failure

→ symptoms due to reduced pumping function

medication: reduction of symptoms, against fluid and salt retention and better prognosis

 

decompensated heart failure (decompensatio cordis)

→ (worsening of) symptoms due to salt and water retention, edema formation

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treatment options:

oral (PO) diuretics: decreased effectiveness (diuretic resistance)

intravenous (IV) diuretics: effective but hospital admission required (high costs, displacement of other care, infections and mental burden)

 

How can we effectively treat patients at home?

the challenge of treating decompensated heart failure effectively in an outpatient setting when oral diuretics lose effectiveness but IV diuretics require hospitalization.